Now how about this for progress? I interviewed a highly respected Bio-Scientist for my next book and asked him whether some patients would respond better to one form of B12 than another. Here’s his reply:
“Cyanocobalamin is the most stable of these compounds, hydroxycobalamin has a tendency to break down and methylcobalamin, as with adenosylcobalamin, is light sensitive (although slightly more stable than adenosylcobalamin). We require more data on the stability of these molecules during the uptake process and the integration of the molecules into cells. Only then will we be able to determine the best form of cobalamin for administration – and even then there is the possibility that there may be some variation with some patients having a preference for different forms”.
That’s something that members of the Pernicious Anaemia Society have been aware of for years – some respond better to one form of artificial B12 than other forms.
My next book is due out in November.